6NR2
Cryo-EM structure of the TRPM8 ion channel in complex with the menthol analog WS-12 and PI(4,5)P2
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005216 | molecular_function | monoatomic ion channel activity |
| A | 0006811 | biological_process | monoatomic ion transport |
| A | 0016020 | cellular_component | membrane |
| A | 0055085 | biological_process | transmembrane transport |
| B | 0005216 | molecular_function | monoatomic ion channel activity |
| B | 0006811 | biological_process | monoatomic ion transport |
| B | 0016020 | cellular_component | membrane |
| B | 0055085 | biological_process | transmembrane transport |
| C | 0005216 | molecular_function | monoatomic ion channel activity |
| C | 0006811 | biological_process | monoatomic ion transport |
| C | 0016020 | cellular_component | membrane |
| C | 0055085 | biological_process | transmembrane transport |
| D | 0005216 | molecular_function | monoatomic ion channel activity |
| D | 0006811 | biological_process | monoatomic ion transport |
| D | 0016020 | cellular_component | membrane |
| D | 0055085 | biological_process | transmembrane transport |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue KXP A 1301 |
| Chain | Residue |
| A | ASN692 |
| A | PHE735 |
| D | LYS605 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue KXS A 1302 |
| Chain | Residue |
| A | TYR745 |
| A | ASP781 |
| A | ARG841 |
| A | ILE845 |
| A | TYR1004 |
| A | ARG1007 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue KXP B 1301 |
| Chain | Residue |
| A | LYS605 |
| B | ASN692 |
| B | PHE735 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue KXS B 1302 |
| Chain | Residue |
| B | TYR745 |
| B | ASP781 |
| B | ARG841 |
| B | ILE845 |
| B | TYR1004 |
| B | ARG1007 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue KXP C 1301 |
| Chain | Residue |
| B | LYS605 |
| C | ASN692 |
| C | PHE735 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue KXS C 1302 |
| Chain | Residue |
| C | TYR745 |
| C | ASP781 |
| C | ARG841 |
| C | ILE845 |
| C | TYR1004 |
| C | ARG1007 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue KXP D 1301 |
| Chain | Residue |
| C | LYS605 |
| D | ASN692 |
| D | PHE735 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue KXS D 1302 |
| Chain | Residue |
| D | TYR745 |
| D | ASP781 |
| D | ARG841 |
| D | ILE845 |
| D | TYR1004 |
| D | ARG1007 |
