6NQ3
Crystal Structure of a SUZ12-RBBP4-PHF19-JARID2 Heterotetrameric Complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E (A, E) | Histone-binding protein RBBP4 | polymer | 439 | 49367.4 | 2 | UniProt (Q09028) Pfam (PF12265) Pfam (PF00400) | Homo sapiens (Human) | Chromatin assembly factor 1 subunit C,CAF-1 subunit C,Chromatin assembly factor I p48 subunit,CAF-I p48,Nucleosome-remodeling factor subunit RBAP48,Retinoblastoma-binding protein 4,RBBP-4,Retinoblastoma-binding protein p48 |
| 2 | B, F (B, F) | Polycomb protein SUZ12 | polymer | 478 | 55686.2 | 2 | UniProt (Q15022) | Homo sapiens (Human) | Chromatin precipitated E2F target 9 protein,ChET 9 protein,Joined to JAZF1 protein,Suppressor of zeste 12 protein homolog |
| 3 | C, G (C, G) | PHD finger protein 19 | polymer | 84 | 9092.8 | 2 | UniProt (Q5T6S3) Pfam (PF14061) | Homo sapiens (Human) | Polycomb-like protein 3,hPCL3 |
| 4 | D, H (D, H) | Protein Jumonji | polymer | 19 | 2257.7 | 2 | UniProt (Q92833) | Homo sapiens | Jumonji/ARID domain-containing protein 2 |
| 5 | I, J (B, F) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) |
Sequence modifications
A, E: 1 - 425 (UniProt: Q09028)
B, F: 76 - 545 (UniProt: Q15022)
C, G: 500 - 580 (UniProt: Q5T6S3)
| PDB | External Database | Details |
|---|---|---|
| Met -13 | - | initiating methionine |
| Ser -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| His -9 | - | expression tag |
| His -8 | - | expression tag |
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| Leu -5 | - | expression tag |
| Val -4 | - | expression tag |
| Pro -3 | - | expression tag |
| Arg -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Trp 546 | - | expression tag |
| Ser 547 | - | expression tag |
| His 548 | - | expression tag |
| Pro 549 | - | expression tag |
| Gln 550 | - | expression tag |
| Phe 551 | - | expression tag |
| Glu 552 | - | expression tag |
| Lys 553 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ser 497 | - | expression tag |
| Asn 498 | - | expression tag |
| Ala 499 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 232808.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 130.8 | |
| All* | Total formula weight | 232939.0 |
