6NP0
Cryo-EM structure of 5HT3A receptor in presence of granisetron
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E | 5-hydroxytryptamine receptor 3A | polymer | 489 | 56284.1 | 5 | UniProt (E9QLC0) Pfam (PF02931) Pfam (PF02932) UniProt (by SIFTS) (P23979) In PDB | Mus musculus (Mouse) | |
| 2 | F, H, J, L, N | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 5 | In PDB GlyTouCan (G15407YE) | |||
| 3 | G, I, K, M, O | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 5 | In PDB GlyTouCan (G42666HT) | |||
| 4 | D, E, A, B, C | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 10 | Chemie (NAG) | |||
| 5 | D, A, B, C | 1-methyl-N-[(1R,5S)-9-methyl-9-azabicyclo[3.3.1]nonan-3-yl]indazole-3-carboxamide | non-polymer | 312.4 | 5 | Chemie (CWB) | |||
| 6 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 281420.5 | |
| Branched | Number of molecules | 10 |
| Total formula weight | 5054.7 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 3809.6 | |
| All* | Total formula weight | 290284.8 |
