6NN8
The structure of human liver pyruvate kinase, hLPYK-S531E
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... | Pyruvate kinase PKLR | polymer | 543 | 58606.2 | 8 | UniProt (P30613) Pfam (PF00224) Pfam (PF02887) In PDB | Homo sapiens (Human) | Pyruvate kinase 1,Pyruvate kinase isozymes L/R,R-type/L-type pyruvate kinase,Red cell/liver pyruvate kinase |
| 2 | C, D, A, E, F... | 1,2-ETHANEDIOL | non-polymer | 62.1 | 41 | Chemie (EDO) | |||
| 3 | water | water | 18.0 | 250 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 3 - 543 (UniProt: P30613)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | expression tag |
| Glu 2 | - | expression tag |
| Glu 531 | Ser 562 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 468849.6 | |
| Non-Polymers* | Number of molecules | 41 |
| Total formula weight | 2544.8 | |
| All* | Total formula weight | 471394.4 |
