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Tranexamic Acid is an Active Site Inhibitor of Urokinase Plasminogen Activator

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Urokinase-type plasminogen activatorpolymer28132008.54UniProt (P00749)
Pfam (PF00089)
Homo sapiens (Human)uPA
2E, G, I, K
(A, B, C, D)
NITRATE IONnon-polymer62.04Chemie (NO3)
3F, H, J, L
(A, B, C, D)
TRANS-4-AMINOMETHYLCYCLOHEXANE-1-CARBOXYLIC ACIDnon-polymer157.24Chemie (AMH)
4M, N, O, P
(A, B, C, D)
waterwater18.0301Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight128033.9
Non-Polymers*Number of molecules8
Total formula weight876.9
All*Total formula weight128910.8
*Water molecules are not included.

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PDB entries from 2025-01-01

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