Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004252 | molecular_function | serine-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| C | 0004252 | molecular_function | serine-type endopeptidase activity |
| C | 0006508 | biological_process | proteolysis |
| D | 0004252 | molecular_function | serine-type endopeptidase activity |
| D | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 1 |
| Details | binding site for residue NO3 A 301 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | binding site for residue AMH A 302 |
| Chain | Residue |
| A | HOH435 |
| A | ASP189 |
| A | SER190 |
| A | SER195 |
| A | VAL213 |
| A | TRP215 |
| A | GLY218 |
| A | GLY226 |
| A | HOH412 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue NO3 B 301 |
| Chain | Residue |
| B | ARG217 |
| B | LEU221 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue AMH B 302 |
| Chain | Residue |
| B | ASP189 |
| B | SER190 |
| B | SER195 |
| B | TRP215 |
| B | GLY218 |
| B | GLY226 |
| B | HOH411 |
| B | HOH440 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue NO3 C 301 |
| Chain | Residue |
| C | ARG217 |
| C | LEU221 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for residue AMH C 302 |
| Chain | Residue |
| C | ASP189 |
| C | SER190 |
| C | SER195 |
| C | VAL213 |
| C | GLY218 |
| C | GLY226 |
| C | HOH417 |
| C | HOH425 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue NO3 D 301 |
| Chain | Residue |
| D | ARG217 |
| D | LEU221 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | binding site for residue AMH D 302 |
| Chain | Residue |
| D | ASP189 |
| D | SER190 |
| D | SER195 |
| D | TRP215 |
| D | GLY218 |
| D | GLY226 |
| D | HOH405 |
| D | HOH440 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. ISATHC |
| Chain | Residue | Details |
| A | ILE53-CYS58 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPLV |
| Chain | Residue | Details |
| A | ASP189-VAL200 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | ACT_SITE: Charge relay system |
| Chain | Residue | Details |
| A | HIS57 | |
| D | HIS57 | |
| D | ASP102 | |
| D | SER195 | |
| A | ASP102 | |
| A | SER195 | |
| B | HIS57 | |
| B | ASP102 | |
| B | SER195 | |
| C | HIS57 | |
| C | ASP102 | |
| C | SER195 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | SITE: Cleavage; during zymogen activation |
| Chain | Residue | Details |
| A | PHE9 | |
| B | PHE11 | |
| C | PHE10 | |
| D | PHE10 | |
| Chain | Residue | Details |
| A | SER146 | |
| B | SER146 | |
| C | SER146 | |
| D | SER146 | |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine |
| Chain | Residue | Details |
| A | ASN145 | |
| B | ASN145 | |
| C | ASN145 | |
| D | ASN145 | |
