6NFJ
Structure of Beta-Klotho in Complex with FGF19 C-terminal peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, D) | Beta-klotho | polymer | 960 | 110389.2 | 2 | UniProt (Q86Z14) Pfam (PF00232) | Homo sapiens (Human) | BetaKlotho,Klotho beta-like protein |
| 2 | B, E (B, E) | Nanobody 30 | polymer | 133 | 14700.3 | 2 | Lama glama | ||
| 3 | C, F (C, F) | Fibroblast growth factor 19 | polymer | 50 | 5553.2 | 2 | UniProt (O95750) | Homo sapiens | FGF-19 |
Sequence modifications
A, D: 30 - 984 (UniProt: Q86Z14)
| PDB | External Database | Details |
|---|---|---|
| Gln 308 | Asn 308 | engineered mutation |
| Gln 611 | Asn 611 | engineered mutation |
| Asn 985 | - | expression tag |
| Leu 986 | - | expression tag |
| Tyr 987 | - | expression tag |
| Phe 988 | - | expression tag |
| Gln 989 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 261285.5 | |
| All* | Total formula weight | 261285.5 |
