6NFJ
Structure of Beta-Klotho in Complex with FGF19 C-terminal peptide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, D | Beta-klotho | polymer | 960 | 110389.2 | 2 | UniProt (Q86Z14) Pfam (PF00232) In PDB | Homo sapiens (Human) | BetaKlotho,Klotho beta-like protein |
2 | B, E | Nanobody 30 | polymer | 133 | 14700.3 | 2 | Lama glama | ||
3 | C, F | Fibroblast growth factor 19 | polymer | 50 | 5553.2 | 2 | UniProt (O95750) In PDB | Homo sapiens | FGF-19 |
Sequence modifications
A, D: 30 - 984 (UniProt: Q86Z14)
PDB | External Database | Details |
---|---|---|
Gln 308 | Asn 308 | engineered mutation |
Gln 611 | Asn 611 | engineered mutation |
Asn 985 | - | expression tag |
Leu 986 | - | expression tag |
Tyr 987 | - | expression tag |
Phe 988 | - | expression tag |
Gln 989 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 261285.5 | |
All* | Total formula weight | 261285.5 |