6NCM
Crystal structure of the human FOXN3 DNA binding domain in complex with a forkhead-like (FHL) DNA sequence
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, B) | Forkhead box protein N3 | polymer | 100 | 11677.5 | 2 | UniProt (O00409) Pfam (PF00250) | Homo sapiens (Human) | Checkpoint suppressor 1 |
| 2 | B (C) | DNA (5'-D(*AP*TP*AP*GP*CP*GP*TP*CP*TP*TP*AP*GP*CP*AP*TP*G)-3') | polymer | 16 | 4913.2 | 1 | synthetic construct | ||
| 3 | C (D) | DNA (5'-D(*TP*CP*AP*TP*GP*CP*TP*AP*AP*GP*AP*CP*GP*CP*TP*A)-3') | polymer | 16 | 4882.2 | 1 | synthetic construct | ||
| 4 | E, F (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | G, H, I, J (A, C, D, B) | water | water | 18.0 | 13 | Chemie (HOH) |
Sequence modifications
A, B: 112 - 210 (UniProt: O00409)
| PDB | External Database | Details |
|---|---|---|
| Gly 111 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 33150.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 48.6 | |
| All* | Total formula weight | 33199.0 |
