6NAZ

Crystal structure of DIRAS 2/3 chimera in complex with GDP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	GTP-binding protein Di-Ras2,GTP-binding protein Di-Ras3,GTP-binding protein Di-Ras2	polymer	199	22495.9	1	UniProt (Q96HU8) UniProt (O95661) Pfam (PF00071)	Homo sapiens (Human)	Distinct subgroup of the Ras family member 2,Distinct subgroup of the Ras family member 3,Rho-related GTP-binding protein RhoI,Distinct subgroup of the Ras family member 2
2	B (A)	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	1	Chemie (GDP)
3	C, D, E (A)	GLYCEROL	non-polymer		92.1	3	Chemie (GOL)
4	F, G, H (A)	1,2-ETHANEDIOL	non-polymer		62.1	3	Chemie (EDO)
5	I (A)	water	water		18.0	13	Chemie (HOH)

Sequence modifications

A: 1 - 61 (UniProt: Q96HU8)
A: 62 - 78 (UniProt: O95661)
A: 79 - 199 (UniProt: Q96HU8)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	22495.9
Non-Polymers*	Number of molecules	7
	Total formula weight	905.7
All*	Total formula weight	23401.6

*Water molecules are not included.