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6NAZ

Crystal structure of DIRAS 2/3 chimera in complex with GDP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
GTP-binding protein Di-Ras2,GTP-binding protein Di-Ras3,GTP-binding protein Di-Ras2polymer19922495.91UniProt (Q96HU8)
UniProt (O95661)
Pfam (PF00071)
Homo sapiens (Human)Distinct subgroup of the Ras family member 2,Distinct subgroup of the Ras family member 3,Rho-related GTP-binding protein RhoI,Distinct subgroup of the Ras family member 2
2B
(A)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.21Chemie (GDP)
PubChem (136073927)
PubChem (135398619)
PubChem (135402030)
PubChem (135431654)
PubChem (135566337)
PubChem (135760556)
PubChem (136026707)
PubChem (136053418)
PubChem (136663964)
PubChem (136664748)
PubChem (136759848)
PubChem (136759849)
PubChem (136759850)
PubChem (136836636)
PubChem (136847074)
PubChem (172898537)
3C, D, E
(A)
GLYCEROLnon-polymer92.13Chemie (GOL)
PubChem (753)
4F, G, H
(A)
1,2-ETHANEDIOLnon-polymer62.13Chemie (EDO)
5I
(A)
waterwater18.013Chemie (HOH)
Sequence modifications
A: 1 - 61 (UniProt: Q96HU8)
A: 62 - 78 (UniProt: O95661)
A: 79 - 199 (UniProt: Q96HU8)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight22495.9
Non-Polymers*Number of molecules7
Total formula weight905.7
All*Total formula weight23401.6
*Water molecules are not included.

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PDB entries from 2026-04-08

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