6N69

rat hPGDS complexed with a quinoline

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Hematopoietic prostaglandin D synthase	polymer	202	23606.2	2	UniProt (O35543) Pfam (PF02798) Pfam (PF14497)	Rattus norvegicus (Rat)	H-PGDS,GST class-sigma,Glutathione S-transferase,Glutathione-dependent PGD synthase,Glutathione-requiring prostaglandin D synthase,Prostaglandin-H2 D-isomerase
2	C, E (A, B)	GLUTATHIONE	non-polymer		307.3	2	Chemie (GSH)
3	D, F (A, B)	quinoline-3-carbonitrile	non-polymer		154.2	2	Chemie (KDV)
4	G, H (A, B)	water	water		18.0	296	Chemie (HOH)

Sequence modifications

A, B: 1 - 199 (UniProt: O35543)

PDB	External Database	Details
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	47212.4
Non-Polymers*	Number of molecules	4
	Total formula weight	923.0
All*	Total formula weight	48135.4

*Water molecules are not included.