6N46
Crystal structure of the cryptic polo box domain of a human activated Plk4
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | Serine/threonine-protein kinase PLK4 | polymer | 249 | 28817.8 | 8 | UniProt (O00444) Pfam (PF18190) Pfam (PF18409) In PDB | Homo sapiens (Human) | Polo-like kinase 4,PLK-4,Serine/threonine-protein kinase 18,Serine/threonine-protein kinase Sak |
Sequence modifications
A, B, C, D, E, F, G, H: -4 - 223 (UniProt: O00444)
PDB | External Database | Details |
---|---|---|
Met -25 | - | initiating methionine |
Gly -24 | - | expression tag |
Ser -23 | - | expression tag |
Ser -22 | - | expression tag |
His -21 | - | expression tag |
His -20 | - | expression tag |
His -19 | - | expression tag |
His -18 | - | expression tag |
His -17 | - | expression tag |
His -16 | - | expression tag |
Ser -15 | - | expression tag |
Ser -14 | - | expression tag |
Gly -13 | - | expression tag |
Leu -12 | - | expression tag |
Val -11 | - | expression tag |
Pro -10 | - | expression tag |
Arg -9 | - | expression tag |
Gly -8 | - | expression tag |
Ser -7 | - | expression tag |
His -6 | - | expression tag |
Met -5 | - | expression tag |
Glu 113 | Ser 698 | conflict |
Glu 115 | Ser 700 | conflict |
Glu 119 | Thr 704 | conflict |
Asp 122 | Thr 707 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 230542.0 | |
All* | Total formula weight | 230542.0 |