6N45
Crystal structure of the cryptic polo box domain of human activated Plk4 variant 1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Chimera protein of Serine/threonine-protein kinase PLK4 and DDB1- and CUL4-associated factor 1 | polymer | 266 | 30590.4 | 2 | UniProt (O00444) UniProt (Q9Y4B6) Pfam (PF18190) Pfam (PF18409) | Homo sapiens (Human) | Polo-like kinase 4,PLK-4,Serine/threonine-protein kinase 18,Serine/threonine-protein kinase Sak,HIV-1 Vpr-binding protein,VprBP,Serine/threonine-protein kinase VPRBP,Vpr-interacting protein |
Sequence modifications
A, B: 581 - 808 (UniProt: O00444)
A, B: 810 - 842 (UniProt: Q9Y4B6)
| PDB | External Database | Details |
|---|---|---|
| Gly 577 | - | expression tag |
| Ala 578 | - | expression tag |
| His 579 | - | expression tag |
| Met 580 | - | expression tag |
| Glu 698 | Ser 698 | conflict |
| Glu 700 | Ser 700 | conflict |
| Glu 704 | Thr 704 | conflict |
| Asp 707 | Thr 707 | conflict |
| Val 809 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 61180.7 | |
| All* | Total formula weight | 61180.7 |
