6MZM
Human TFIID bound to promoter DNA and TFIIA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Transcription initiation factor TFIID subunit 1, TAF1 | polymer | 496 | 57193.7 | 1 | Pfam (PF12157) UniProt (by SIFTS) (P21675) | Homo sapiens (Human) | |
| 2 | B (B) | Transcription initiation factor TFIID subunit 2, TAF2 | polymer | 1199 | 137160.0 | 1 | UniProt (Q6P1X5) | Homo sapiens (Human) | 150 kDa cofactor of initiator function |
| 3 | C (D) | Transcription initiation factor TFIID subunit 4, TAF4 | polymer | 1025 | 104052.1 | 1 | UniProt (O00268) Pfam (PF07531) Pfam (PF05236) | Homo sapiens (Human) | |
| 4 | D (G) | Transcription initiation factor TFIID subunit 5,TAF5 | polymer | 800 | 85785.2 | 1 | UniProt (Q15542) Pfam (PF00400) Pfam (PF04494) | Homo sapiens (Human) | Transcription initiation factor TFIID 100 kDa subunit,TAFII100 |
| 5 | E (H) | Transcription initiation factor TFIID subunit 6 | polymer | 677 | 72749.3 | 1 | UniProt (P49848) Pfam (PF02969) Pfam (PF07571) | Homo sapiens (Human) | RNA polymerase II TBP-associated factor subunit E |
| 6 | F (I) | Transcription initiation factor TFIID subunit 6 | polymer | 677 | 72365.8 | 1 | UniProt (P49848) Pfam (PF02969) Pfam (PF07571) | Homo sapiens (Human) | Transcription initiation factor TFIID 70 kDa subunit |
| 7 | G (J) | Transcription initiation factor TFIID subunit 7 | polymer | 349 | 40325.1 | 1 | UniProt (Q15545) Pfam (PF04658) | Homo sapiens (Human) | RNA polymerase II TBP-associated factor subunit F,Transcription initiation factor TFIID 55 kDa subunit,TAFII55 |
| 8 | H (K) | Transcription initiation factor TFIID subunit 8, TAF8 | polymer | 310 | 32975.3 | 1 | UniProt (Q7Z7C8) Pfam (PF07524) Pfam (PF10406) | Homo sapiens (Human) | Protein taube nuss,TBP-associated factor 43 kDa,TBP-associated factor 8,Transcription initiation factor TFIID 43 kDa subunit,hTAFII43,Protein taube nuss,TBP-associated factor 43 kDa,TBP-associated factor 8 |
| 9 | I (L) | Transcription initiation factor TFIID subunit 9, TAF9 | polymer | 264 | 28830.7 | 1 | UniProt (Q16594) Pfam (PF02291) | Homo sapiens (Human) | RNA polymerase II TBP-associated factor subunit G,STAF31/32,Transcription initiation factor TFIID 31 kDa subunit,TAFII31,Transcription initiation factor TFIID 32 kDa subunit,TAFII32 |
| 10 | J (O) | Transcription initiation factor TFIID subunit 10 | polymer | 218 | 21731.2 | 1 | UniProt (Q12962) Pfam (PF03540) | Homo sapiens (Human) | STAF28,Transcription initiation factor TFIID 30 kDa subunit,TAFII30 |
| 11 | K (R) | Transcription initiation factor TFIID subunit 12 | polymer | 161 | 17948.5 | 1 | UniProt (Q16514) Pfam (PF03847) | Homo sapiens (Human) | Transcription initiation factor TFIID 20/15 kDa subunits,TAFII20/TAFII15 |
| 12 | L (T) | TATA-box-binding protein | polymer | 339 | 37729.9 | 1 | UniProt (P20226) Pfam (PF00352) | Homo sapiens (Human) | TATA sequence-binding protein,TATA-binding factor,TATA-box factor,Transcription initiation factor TFIID TBP subunit |
| 13 | M (U) | SCP DNA (80-MER) | polymer | 80 | 24498.6 | 1 | Homo sapiens | ||
| 14 | N (V) | SCP DNA (80-MER) | polymer | 80 | 24854.8 | 1 | Homo sapiens | ||
| 15 | O (W) | Transcription initiation factor IIA subunit 1 | polymer | 90 | 10675.2 | 1 | Pfam (PF03153) UniProt (by SIFTS) (P52655) | Homo sapiens (Human) | General transcription factor IIA subunit 1,TFIIAL,Transcription initiation factor TFIIA 42 kDa subunit,TFIIA-42 |
| 16 | P (X) | Transcription initiation factor IIA subunit 2 | polymer | 97 | 11275.8 | 1 | UniProt (P52657) Pfam (PF02268) Pfam (PF02751) | Homo sapiens (Human) | General transcription factor IIA subunit 2,TFIIA p12 subunit,TFIIAS,Transcription initiation factor IIA gamma chain,TFIIA-gamma |
| 17 | Q (Z) | Unk | polymer | 238 | 20272.9 | 1 | Homo sapiens |
Sequence modifications
G: 1 - 496 (UniProt: Q15542)
G: 497 - 536 (PDB: 6MZM)
G: 537 - 800 (UniProt: Q15542)
I: 1 - 206 (UniProt: P49848)
I: 207 - 216 (PDB: 6MZM)
I: 217 - 677 (UniProt: P49848)
K: 1 - 310 (UniProt: Q7Z7C8)
K: 121 - 170 (PDB: 6MZM)
K: 171 - 310 (PDB: 6MZM)
L: 1 - 264 (UniProt: Q16594)
L: 109 - 116 (PDB: 6MZM)
L: 117 - 264 (PDB: 6MZM)
G: 497 - 536 (PDB: 6MZM)
G: 537 - 800 (UniProt: Q15542)
I: 1 - 206 (UniProt: P49848)
I: 207 - 216 (PDB: 6MZM)
I: 217 - 677 (UniProt: P49848)
K: 1 - 310 (UniProt: Q7Z7C8)
K: 121 - 170 (PDB: 6MZM)
K: 171 - 310 (PDB: 6MZM)
L: 1 - 264 (UniProt: Q16594)
L: 109 - 116 (PDB: 6MZM)
L: 117 - 264 (PDB: 6MZM)
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 17 |
| Total formula weight | 800424.3 | |
| All* | Total formula weight | 800424.3 |
