6MWG

NavAb Voltage-gated Sodium Channel, residues 1-239, with mutation T206V

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (B)	Ion transport protein	polymer	257	29787.3	1	UniProt (A8EVM5) Pfam (PF00520) Pfam (PF08016)	Arcobacter butzleri (strain RM4018)
2	B, C, D, E (B)	1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE	non-polymer		678.9	4	Chemie (PX4)
3	F (B)	ACETATE ION	non-polymer		59.0	1	Chemie (ACT)
4	G, H (B)	3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE	non-polymer		614.9	2	Chemie (CPS)
5	I (B)	water	water		18.0	24	Chemie (HOH)

Sequence modifications

B: 2001 - 2239 (UniProt: A8EVM5)

PDB	External Database	Details
Met 1983	-	initiating methionine
Asp 1984	-	expression tag
Tyr 1985	-	expression tag
Lys 1986	-	expression tag
Asp 1987	-	expression tag
Asp 1988	-	expression tag
Asp 1989	-	expression tag
Asp 1990	-	expression tag
Lys 1991	-	expression tag
Gly 1992	-	expression tag
Ser 1993	-	expression tag
Leu 1994	-	expression tag
Val 1995	-	expression tag
Pro 1996	-	expression tag
Arg 1997	-	expression tag
Gly 1998	-	expression tag
Ser 1999	-	expression tag
His 2000	-	expression tag
Val 2206	Thr 206	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	29787.3
Non-Polymers*	Number of molecules	7
	Total formula weight	4004.6
All*	Total formula weight	33791.9

*Water molecules are not included.