6MWG
NavAb Voltage-gated Sodium Channel, residues 1-239, with mutation T206V
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0001518 | cellular_component | voltage-gated sodium channel complex |
| B | 0005216 | molecular_function | monoatomic ion channel activity |
| B | 0005248 | molecular_function | voltage-gated sodium channel activity |
| B | 0005261 | molecular_function | monoatomic cation channel activity |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006811 | biological_process | monoatomic ion transport |
| B | 0016020 | cellular_component | membrane |
| B | 0035725 | biological_process | sodium ion transmembrane transport |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0055085 | biological_process | transmembrane transport |
| B | 0098655 | biological_process | monoatomic cation transmembrane transport |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | binding site for residue PX4 B 2301 |
| Chain | Residue |
| B | PHE2141 |
| B | MET2209 |
| B | PX42302 |
| B | HOH2412 |
| B | GLY2164 |
| B | GLU2165 |
| B | PHE2167 |
| B | TYR2168 |
| B | PHE2171 |
| B | MET2188 |
| B | PRO2192 |
| B | TRP2195 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | binding site for residue PX4 B 2302 |
| Chain | Residue |
| B | ILE2027 |
| B | GLY2030 |
| B | LEU2031 |
| B | SER2034 |
| B | THR2138 |
| B | TYR2142 |
| B | THR2162 |
| B | LEU2163 |
| B | GLY2164 |
| B | PX42301 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue PX4 B 2303 |
| Chain | Residue |
| B | ILE2097 |
| B | PHE2144 |
| B | LEU2151 |
| B | ARG2155 |
| B | TYR2191 |
| B | TYR2193 |
| B | ALA2194 |
| B | HOH2404 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue PX4 B 2304 |
| Chain | Residue |
| B | PRO2075 |
| B | TRP2076 |
| B | PHE2079 |
| B | SER2121 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | binding site for residue ACT B 2305 |
| Chain | Residue |
| B | SER2178 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | binding site for residue CPS B 2306 |
| Chain | Residue |
| B | ILE2119 |
| B | VAL2126 |
| B | GLY2129 |
| B | LEU2212 |
| B | ILE2216 |
| B | ASP2219 |
| B | ILE2223 |
| B | HOH2409 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue CPS B 2307 |
| Chain | Residue |
| B | SER2125 |
| B | VAL2126 |
| B | ILE2223 |
| B | HOH2410 |
