6MVY
NavAb voltage-gated sodium channel, residues 1-226, crystallized in the presence of Class 1B Anti-arrhythmic drug Lidocaine
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Ion transport protein | polymer | 244 | 28202.6 | 2 | UniProt (A8EVM5) Pfam (PF00520) In PDB | Arcobacter butzleri (strain RM4018) | |
2 | A, B | 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE | non-polymer | 678.9 | 8 | Chemie (PX4) | |||
3 | A, B | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
4 | water | water | 18.0 | 39 | Chemie (HOH) |
Sequence modifications
A, B: 1001 - 1226 (UniProt: A8EVM5)
PDB | External Database | Details |
---|---|---|
Met 983 | - | initiating methionine |
Asp 984 | - | expression tag |
Tyr 985 | - | expression tag |
Lys 986 | - | expression tag |
Asp 987 | - | expression tag |
Asp 988 | - | expression tag |
Asp 989 | - | expression tag |
Asp 990 | - | expression tag |
Lys 991 | - | expression tag |
Gly 992 | - | expression tag |
Ser 993 | - | expression tag |
Leu 994 | - | expression tag |
Val 995 | - | expression tag |
Pro 996 | - | expression tag |
Arg 997 | - | expression tag |
Gly 998 | - | expression tag |
Ser 999 | - | expression tag |
His 1000 | - | expression tag |
Cys 1217 | Ile 217 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 56405.2 | |
Non-Polymers* | Number of molecules | 10 |
Total formula weight | 5623.6 | |
All* | Total formula weight | 62028.8 |