6MTG
A Single Reactive Noncanonical Amino Acid is Able to Dramatically Stabilize Protein Structure
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Homoserine O-succinyltransferase | polymer | 302 | 35084.3 | 2 | UniProt (P07623) Pfam (PF04204) | Escherichia coli (strain K12) | HST,Homoserine transsuccinylase,HTS |
| 2 | C, D (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 3 | E, F, H, I, J (A, B) | FORMIC ACID | non-polymer | 46.0 | 5 | Chemie (FMT) | |||
| 4 | G (B) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | K, L (A, B) | water | water | 18.0 | 544 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 296 (UniProt: P07623)
| PDB | External Database | Details |
|---|---|---|
| Ile 257 | Pro 257 | engineered mutation |
| His 297 | - | expression tag |
| His 298 | - | expression tag |
| His 299 | - | expression tag |
| His 300 | - | expression tag |
| His 301 | - | expression tag |
| His 302 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 70168.7 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 534.5 | |
| All* | Total formula weight | 70703.1 |
