6MSN
Crystal structure of cytosolic fumarate hydratase from Leishmania major in a complex with inhibitor thiomalate
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | fumarate hydratase | polymer | 604 | 66513.5 | 2 | UniProt (E9AE57) Pfam (PF05681) Pfam (PF05683) In PDB | Leishmania major | |
2 | A, B | IRON/SULFUR CLUSTER | non-polymer | 351.6 | 2 | Chemie (SF4) | |||
3 | A, B | (2S)-2-sulfanylbutanedioic acid | non-polymer | 150.2 | 2 | Chemie (JYD) | |||
4 | water | water | 18.0 | 821 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 568 (UniProt: E9AE57)
PDB | External Database | Details |
---|---|---|
Met -35 | - | initiating methionine |
Gly -34 | - | expression tag |
Ser -33 | - | expression tag |
Ser -32 | - | expression tag |
His -31 | - | expression tag |
His -30 | - | expression tag |
His -29 | - | expression tag |
His -28 | - | expression tag |
His -27 | - | expression tag |
His -26 | - | expression tag |
Ser -25 | - | expression tag |
Ser -24 | - | expression tag |
Gly -23 | - | expression tag |
Leu -22 | - | expression tag |
Val -21 | - | expression tag |
Pro -20 | - | expression tag |
Arg -19 | - | expression tag |
Gly -18 | - | expression tag |
Ser -17 | - | expression tag |
His -16 | - | expression tag |
Met -15 | - | expression tag |
Ala -14 | - | expression tag |
Ser -13 | - | expression tag |
Met -12 | - | expression tag |
Thr -11 | - | expression tag |
Gly -10 | - | expression tag |
Gly -9 | - | expression tag |
Gln -8 | - | expression tag |
Gln -7 | - | expression tag |
Met -6 | - | expression tag |
Gly -5 | - | expression tag |
Arg -4 | - | expression tag |
Gly -3 | - | expression tag |
Ser -2 | - | expression tag |
Glu -1 | - | expression tag |
Phe 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 133026.9 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1003.6 | |
All* | Total formula weight | 134030.5 |