6MRG

FAAH bound to non covalent inhibitor

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Fatty-acid amide hydrolase 1	polymer	580	63779.3	4	UniProt (P97612) Pfam (PF01425)	Rattus norvegicus (Rat)	Anandamide amidohydrolase 1,Oleamide hydrolase 1
2	E, F, G, H (A, B, C, D)	(1R)-2-{[6-(2,3-dihydro-1,4-benzodioxin-6-yl)pyrimidin-4-yl]amino}-1-phenylethan-1-ol	non-polymer		349.4	4	Chemie (JXV)
3	I, J, K, L (A, B, C, D)	water	water		18.0	14	Chemie (HOH)

Sequence modifications

A, B, C, D: 32 - 579 (UniProt: P97612)

PDB	External Database	Details
Gly 0	-	expression tag
Ser 1	-	expression tag
Gly 2	-	expression tag
Met 3	-	expression tag
Lys 4	-	expression tag
Glu 5	-	expression tag
Thr 6	-	expression tag
Ala 7	-	expression tag
Ala 8	-	expression tag
Ala 9	-	expression tag
Lys 10	-	expression tag
Phe 11	-	expression tag
Glu 12	-	expression tag
Arg 13	-	expression tag
Gln 14	-	expression tag
His 15	-	expression tag
Met 16	-	expression tag
Asp 17	-	expression tag
Ser 18	-	expression tag
Pro 19	-	expression tag
Asp 20	-	expression tag
Leu 21	-	expression tag
Gly 22	-	expression tag
Thr 23	-	expression tag
Asp 24	-	expression tag
Asp 25	-	expression tag
Asp 26	-	expression tag
Asp 27	-	expression tag
Lys 28	-	expression tag
Ala 29	-	expression tag
Met 30	-	expression tag
Glu 31	-	expression tag
Phe 192	Leu 192	conflict
Tyr 194	Phe 194	conflict
Thr 377	Ala 377	conflict
Asn 435	Ser 435	conflict
Val 491	Ile 491	conflict
Met 495	Val 495	conflict

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	255117.1
Non-Polymers*	Number of molecules	4
	Total formula weight	1397.5
All*	Total formula weight	256514.7

*Water molecules are not included.