6MNH
ULK1 Unc-51 like autophagy activating kinase in complex with inhibitor BTC
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein kinase ULK1 | polymer | 287 | 32556.7 | 1 | UniProt (O75385) Pfam (PF00069) | Homo sapiens (Human) | Autophagy-related protein 1 homolog,hATG1,Unc-51-like kinase 1 |
| 2 | B (A) | N-[(2R)-3-methylbutan-2-yl]-1H-benzotriazole-6-carboxamide | non-polymer | 232.3 | 1 | Chemie (JVD) | |||
| 3 | C (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 4 | D, E (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 5 | F (A) | water | water | 18.0 | 225 | Chemie (HOH) |
Sequence modifications
A: 6 - 290 (UniProt: O75385)
| PDB | External Database | Details |
|---|---|---|
| Ser 4 | - | expression tag |
| Leu 5 | - | expression tag |
| Ala 195 | Ser 195 | engineered mutation |
| Ala 224 | Ser 224 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32556.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 381.3 | |
| All* | Total formula weight | 32938.0 |
