6MNH
ULK1 Unc-51 like autophagy activating kinase in complex with inhibitor BTC
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Serine/threonine-protein kinase ULK1 | polymer | 287 | 32556.7 | 1 | UniProt (O75385) Pfam (PF00069) In PDB | Homo sapiens (Human) | Autophagy-related protein 1 homolog,hATG1,Unc-51-like kinase 1 |
2 | A | N-[(2R)-3-methylbutan-2-yl]-1H-benzotriazole-6-carboxamide | non-polymer | 232.3 | 1 | Chemie (JVD) | |||
3 | A | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
4 | A | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
5 | water | water | 18.0 | 225 | Chemie (HOH) |
Sequence modifications
A: 6 - 290 (UniProt: O75385)
PDB | External Database | Details |
---|---|---|
Ser 4 | - | expression tag |
Leu 5 | - | expression tag |
Ala 195 | Ser 195 | engineered mutation |
Ala 224 | Ser 224 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 32556.7 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 381.3 | |
All* | Total formula weight | 32938.0 |