6MN4
Crystal structure of aminoglycoside acetyltransferase AAC(3)-IVa, H154A mutant, in complex with apramycin
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | Aminoglycoside N(3)-acetyltransferase, AAC(3)-IVa | polymer | 260 | 28057.1 | 6 | UniProt (Q306W4) Pfam (PF02522) In PDB | Escherichia coli | |
2 | E, A, F, B, C... | APRAMYCIN | non-polymer | 539.6 | 6 | Chemie (AM2) | |||
3 | A, B, C, D | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
4 | E, A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
5 | E, F, A, B, C... | PHOSPHATE ION | non-polymer | 95.0 | 6 | Chemie (PO4) | |||
6 | D, E, F, A, B... | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 6 | Chemie (EPE) | |||
7 | D, E | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
8 | water | water | 18.0 | 339 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 1 - 258 (UniProt: Q306W4)
PDB | External Database | Details |
---|---|---|
Gln -1 | - | expression tag |
Gly 0 | - | expression tag |
Ala 154 | His 154 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 168342.4 | |
Non-Polymers* | Number of molecules | 30 |
Total formula weight | 6055.4 | |
All* | Total formula weight | 174397.8 |