6MN0
Crystal structure of meta-AAC0038, an environmental aminoglycoside resistance enzyme, H168A mutant in complex with acetyl-CoA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Aminoglycoside N(3)-acetyltransferase | polymer | 263 | 28654.3 | 6 | UniProt (A0A059X981) Pfam (PF02522) | uncultured bacterium | |
| 2 | BA, G, HA, P, QA... (D, A, E, B, F...) | ACETYL COENZYME *A | non-polymer | 809.6 | 6 | Chemie (ACO) | |||
| 3 | H, RA, V (A, F, C) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 4 | CA, DA, EA, I, IA (D, A, E) | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
| 5 | FA, GA, J, JA, K... (D, A, E, B, F...) | SULFATE ION | non-polymer | 96.1 | 21 | Chemie (SO4) | |||
| 6 | AA, M, N, O, PA... (C, A, E, B, F) | 3,6,9,12,15,18,21,24,27,30,33,36,39-TRIDECAOXAHENTETRACONTANE-1,41-DIOL | non-polymer | 634.8 | 8 | Chemie (PE3) | |||
| 7 | AB, BB, CB, XA, YA... (D, E, F, A, B...) | water | water | 18.0 | 1645 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 2 - 263 (UniProt: A0A059X981)
| PDB | External Database | Details |
|---|---|---|
| Val 1 | - | expression tag |
| Ala 168 | His 168 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 171926.1 | |
| Non-Polymers* | Number of molecules | 43 |
| Total formula weight | 12519.6 | |
| All* | Total formula weight | 184445.7 |
