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6MID

Cryo-EM structure of the ZIKV virion in complex with Fab fragments of the potently neutralizing human monoclonal antibody ZIKV-195

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C, E
(A, C, E)
E proteinpolymer50454444.13UniProt (A0A024B7W1)
Pfam (PF00869)
Pfam (PF02832)
Pfam (PF21659)
Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013) (ZIKV)
2B, D, F
(B, D, F)
M proteinpolymer758496.93UniProt (A0A024B7W1)
Pfam (PF01004)
Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013) (ZIKV)
3G
(H)
monoclonal antibody ZIKV-195 heavy chainpolymer12814148.71Homo sapiens (Human)
4H
(L)
monoclonal antibody ZIKV-195 light chainpolymer11011750.91UniProt (A0A0B4J1U3)
Pfam (PF07686)
Homo sapiens (Human)
5I, J, K
(G, I, J)
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched424.43In PDB
GlyTouCan (G42666HT)
Sequence modifications
L: 1 - 96 (UniProt: A0A0B4J1U3)
L: 97 - 110 (PDB: 6MID)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight214722.4
BranchedNumber of molecules3
Total formula weight1273.2
All*Total formula weight215995.6
*Water molecules are not included.

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PDB entries from 2025-10-29

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