6MID
Cryo-EM structure of the ZIKV virion in complex with Fab fragments of the potently neutralizing human monoclonal antibody ZIKV-195
Summary for 6MID
Entry DOI | 10.2210/pdb6mid/pdb |
EMDB information | 9131 |
Descriptor | E protein, M protein, monoclonal antibody ZIKV-195 heavy chain, ... (5 entities in total) |
Functional Keywords | virus, monoclonal antibody, complex, virus-immune system complex, virus/immune system |
Biological source | Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013) (ZIKV) More |
Total number of polymer chains | 8 |
Total formula weight | 215995.65 |
Authors | Long, F.,Rossmann, M.G. (deposition date: 2018-09-19, release date: 2019-01-16, Last modification date: 2020-07-29) |
Primary citation | Long, F.,Doyle, M.,Fernandez, E.,Miller, A.S.,Klose, T.,Sevvana, M.,Bryan, A.,Davidson, E.,Doranz, B.J.,Kuhn, R.J.,Diamond, M.S.,Crowe Jr., J.E.,Rossmann, M.G. Structural basis of a potent human monoclonal antibody against Zika virus targeting a quaternary epitope. Proc. Natl. Acad. Sci. U.S.A., 116:1591-1596, 2019 Cited by PubMed: 30642974DOI: 10.1073/pnas.1815432116 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4 Å) |
Structure validation
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