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6MFS

Mouse talin1 residues 1-138 fused to residues 169-400 in complex with phosphatidylinositol 4,5-bisphosphate (PIP2)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Talin-1 fusionpolymer37242970.51UniProt (P26039)
Pfam (PF16511)
Pfam (PF00373)
Pfam (PF02174)
Mus musculus (Mouse)
2B
(A)
[(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoatenon-polymer746.61Chemie (PIO)
3C, D, E
(A)
PHOSPHATE IONnon-polymer95.03Chemie (PO4)
4F
(A)
waterwater18.0122Chemie (HOH)
Sequence modifications
A: 1 - 138 (UniProt: P26039)
PDBExternal DatabaseDetails
Gly -1-expression tag
Pro 0-expression tag
Lys 137Lys 137linker
Lys 138Lys 138linker
A: 169 - 400 (UniProt: P26039)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight42970.5
Non-Polymers*Number of molecules4
Total formula weight1031.5
All*Total formula weight44002.0
*Water molecules are not included.

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PDB entries from 2025-12-10

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