6MCK

p97 D1D2 with CB5083 bound

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	Transitional endoplasmic reticulum ATPase	polymer	606	67172.3	12	UniProt (P55072) Pfam (PF00004) Pfam (PF17862) In PDB	Homo sapiens (Human)	TER ATPase,15S Mg(2+)-ATPase p97 subunit,Valosin-containing protein,VCP
2	A, B, C, D, E...	1-[4-(benzylamino)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-2-yl]-2-methyl-1H-indole-4-carboxamide	non-polymer		413.5	12	Chemie (JDP)
3		water	water		18.0	32	Chemie (HOH)

Sequence modifications

A, B, C, D, E, F, G, H, I, J, K, L: 210 - 806 (UniProt: P55072)

PDB	External Database	Details
Met 209	-	expression tag
Arg 807	-	expression tag
Ser 808	-	expression tag
His 809	-	expression tag
His 810	-	expression tag
His 811	-	expression tag
His 812	-	expression tag
His 813	-	expression tag
His 814	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	806067.5
Non-Polymers*	Number of molecules	12
	Total formula weight	4961.7
All*	Total formula weight	811029.1

*Water molecules are not included.