6MCK

p97 D1D2 with CB5083 bound

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005524	molecular_function	ATP binding
A	0016887	molecular_function	ATP hydrolysis activity
B	0005524	molecular_function	ATP binding
B	0016887	molecular_function	ATP hydrolysis activity
C	0005524	molecular_function	ATP binding
C	0016887	molecular_function	ATP hydrolysis activity
D	0005524	molecular_function	ATP binding
D	0016887	molecular_function	ATP hydrolysis activity
E	0005524	molecular_function	ATP binding
E	0016887	molecular_function	ATP hydrolysis activity
F	0005524	molecular_function	ATP binding
F	0016887	molecular_function	ATP hydrolysis activity
G	0005524	molecular_function	ATP binding
G	0016887	molecular_function	ATP hydrolysis activity
H	0005524	molecular_function	ATP binding
H	0016887	molecular_function	ATP hydrolysis activity
I	0005524	molecular_function	ATP binding
I	0016887	molecular_function	ATP hydrolysis activity
J	0005524	molecular_function	ATP binding
J	0016887	molecular_function	ATP hydrolysis activity
K	0005524	molecular_function	ATP binding
K	0016887	molecular_function	ATP hydrolysis activity
L	0005524	molecular_function	ATP binding
L	0016887	molecular_function	ATP hydrolysis activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	binding site for residue JDP A 900

Chain	Residue
A	ASP478
A	GLY684
A	ALA685
A	THR688
A	ILE479
A	LEU482
A	GLY523
A	LEU526
A	ILE656
A	ALA659
A	ASN660
A	ARG662

---

site_id	AC2
Number of Residues	14
Details	binding site for residue JDP B 900

Chain	Residue
B	VAL474
B	ASP478
B	ILE479
B	LEU482
B	CYS522
B	GLY523
B	LEU526
B	ILE656
B	ALA659
B	ASN660
B	ARG662
B	GLY684
B	ALA685
B	THR688

---

site_id	AC3
Number of Residues	12
Details	binding site for residue JDP C 900

Chain	Residue
C	VAL474
C	ASP478
C	ILE479
C	LEU482
C	GLY523
C	LEU526
C	ILE656
C	ALA659
C	ARG662
C	GLY684
C	ALA685
C	THR688

---

site_id	AC4
Number of Residues	14
Details	binding site for residue JDP D 900

Chain	Residue
D	ASP478
D	ILE479
D	LEU482
D	CYS522
D	GLY523
D	LEU526
D	SER652
D	ILE656
D	ALA659
D	ASN660
D	ARG662
D	GLY684
D	ALA685
D	THR688

---

site_id	AC5
Number of Residues	14
Details	binding site for residue JDP E 900

Chain	Residue
E	ASP478
E	ILE479
E	LEU482
E	CYS522
E	GLY523
E	LEU526
E	ALA655
E	ILE656
E	ALA659
E	ASN660
E	ARG662
E	GLY684
E	ALA685
E	THR688

---

site_id	AC6
Number of Residues	11
Details	binding site for residue JDP F 900

Chain	Residue
F	ASP478
F	ILE479
F	LEU482
F	GLY523
F	LEU526
F	ILE656
F	ALA659
F	ARG662
F	GLY684
F	ALA685
F	THR688

---

site_id	AC7
Number of Residues	11
Details	binding site for residue JDP G 900

Chain	Residue
G	ASP478
G	ILE479
G	GLY523
G	LEU526
G	ILE656
G	ALA659
G	ASN660
G	ARG662
G	GLY684
G	ALA685
G	THR688

---

site_id	AC8
Number of Residues	15
Details	binding site for residue JDP H 900

Chain	Residue
H	ARG662
H	GLY684
H	ALA685
H	THR688
H	VAL474
H	ASP478
H	ILE479
H	LEU482
H	CYS522
H	GLY523
H	LEU526
H	LEU527
H	ILE656
H	ALA659
H	ASN660

---

site_id	AC9
Number of Residues	13
Details	binding site for residue JDP I 900

Chain	Residue
I	ASP478
I	ILE479
I	LEU482
I	CYS522
I	GLY523
I	LEU526
I	ILE656
I	ALA659
I	ASN660
I	ARG662
I	GLY684
I	ALA685
I	THR688

---

site_id	AD1
Number of Residues	13
Details	binding site for residue JDP J 900

Chain	Residue
J	ASP478
J	ILE479
J	LEU482
J	GLY523
J	LEU526
J	SER652
J	ILE656
J	ALA659
J	ASN660
J	ARG662
J	GLY684
J	ALA685
J	THR688

---

site_id	AD2
Number of Residues	13
Details	binding site for residue JDP K 900

Chain	Residue
K	ASP478
K	ILE479
K	LEU482
K	CYS522
K	GLY523
K	LEU526
K	ILE656
K	ALA659
K	ASN660
K	ARG662
K	GLY684
K	ALA685
K	THR688

---

site_id	AD3
Number of Residues	11
Details	binding site for residue JDP L 900

Chain	Residue
L	ASP478
L	ILE479
L	GLY523
L	LEU526
L	ILE656
L	ALA659
L	ASN660
L	ARG662
L	GLY684
L	ALA685
L	THR688

---

Functional Information from PROSITE/UniProt

site_id	PS00674
Number of Residues	19
Details	AAA AAA-protein family signature. ViVMaATNrpnsIDpALr.R

Chain	Residue	Details
A	VAL341-ARG359
A	VAL617-ARG635

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	96
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20512113","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	60
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q01853","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	12
Details	Modified residue: {"description":"N6,N6,N6-trimethyllysine; by VCPKMT","evidences":[{"source":"PubMed","id":"22948820","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23349634","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	24
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	36
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q01853","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	12
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"Q01853","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---