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6MBP

GLP Methyltransferase with Inhibitor EML741- P3121 Crystal Form

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Histone-lysine N-methyltransferase EHMT1polymer26130232.42UniProt (Q9H9B1)
Pfam (PF05033)
Pfam (PF00856)
Homo sapiens (Human)Euchromatic histone-lysine N-methyltransferase 1,Eu-HMTase1,G9a-like protein 1,GLP1,Histone H3-K9 methyltransferase 5,H3-K9-HMTase 5,Lysine N-methyltransferase 1D
2C, P
(A, B)
2-cyclohexyl-7-methoxy-N-[1-(propan-2-yl)piperidin-4-yl]-8-[3-(pyrrolidin-1-yl)propoxy]-3H-1,4-benzodiazepin-5-aminenon-polymer523.82Chemie (JDG)
3D, E, F, G, Q...
(A, B)
ZINC IONnon-polymer65.48Chemie (ZN)
4H, U
(A, B)
S-ADENOSYL-L-HOMOCYSTEINEnon-polymer384.42Chemie (SAH)
5I, J, K, L, M...
(A, B)
1,2-ETHANEDIOLnon-polymer62.112Chemie (EDO)
6AA, BA
(A, B)
waterwater18.0414Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight60464.7
Non-Polymers*Number of molecules24
Total formula weight3084.4
All*Total formula weight63549.2
*Water molecules are not included.

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PDB entries from 2025-10-22

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