Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0002039 | molecular_function | p53 binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0016279 | molecular_function | protein-lysine N-methyltransferase activity |
| A | 0042054 | molecular_function | histone methyltransferase activity |
| B | 0002039 | molecular_function | p53 binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0016279 | molecular_function | protein-lysine N-methyltransferase activity |
| B | 0042054 | molecular_function | histone methyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | binding site for residue JDG A 2001 |
| Chain | Residue |
| A | TYR1124 |
| A | TYR1211 |
| A | ARG1214 |
| A | PHE1215 |
| A | LYS1219 |
| A | HOH2109 |
| A | HOH2191 |
| A | ASP1131 |
| A | ALA1134 |
| A | ASP1135 |
| A | ARG1137 |
| A | ASP1140 |
| A | SER1141 |
| A | LEU1143 |
| A | ASP1145 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 2002 |
| Chain | Residue |
| A | CYS1037 |
| A | CYS1074 |
| A | CYS1080 |
| A | CYS1084 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 2003 |
| Chain | Residue |
| A | CYS1031 |
| A | CYS1044 |
| A | CYS1074 |
| A | CYS1078 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 2004 |
| Chain | Residue |
| A | CYS1031 |
| A | CYS1033 |
| A | CYS1037 |
| A | CYS1042 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 2005 |
| Chain | Residue |
| A | CYS1172 |
| A | CYS1225 |
| A | CYS1227 |
| A | CYS1232 |
| site_id | AC6 |
| Number of Residues | 16 |
| Details | binding site for residue SAH A 2006 |
| Chain | Residue |
| A | MET1105 |
| A | TRP1107 |
| A | SER1141 |
| A | TYR1142 |
| A | ARG1166 |
| A | PHE1167 |
| A | ASN1169 |
| A | HIS1170 |
| A | TYR1211 |
| A | PHE1215 |
| A | CYS1225 |
| A | ARG1226 |
| A | HOH2127 |
| A | HOH2139 |
| A | HOH2222 |
| A | HOH2253 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 2007 |
| Chain | Residue |
| A | CYS1033 |
| A | ILE1034 |
| A | ASP1035 |
| A | SER1039 |
| A | ASN1041 |
| B | LEU1047 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 2008 |
| Chain | Residue |
| A | ASN1013 |
| A | LEU1128 |
| A | HIS1185 |
| A | PHE1190 |
| A | ARG1192 |
| A | HOH2102 |
| A | HOH2155 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 2009 |
| Chain | Residue |
| A | MET1065 |
| A | PRO1174 |
| A | HOH2103 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 2010 |
| Chain | Residue |
| A | GLY986 |
| A | GLU988 |
| A | ARG989 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 2011 |
| Chain | Residue |
| A | TYR1161 |
| B | ALA1077 |
| B | HOH1464 |
| site_id | AD3 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 2012 |
| Chain | Residue |
| A | ALA1077 |
| A | HOH2106 |
| A | HOH2227 |
| site_id | AD4 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 2013 |
| Chain | Residue |
| A | ARG985 |
| A | TYR987 |
| A | LYS1008 |
| A | TYR1009 |
| A | HOH2236 |
| B | CYS1078 |
| B | SER1079 |
| B | CYS1080 |
| site_id | AD5 |
| Number of Residues | 16 |
| Details | binding site for residue JDG B 1301 |
| Chain | Residue |
| B | TYR1124 |
| B | ASP1131 |
| B | ASP1135 |
| B | ARG1137 |
| B | GLU1138 |
| B | ASP1140 |
| B | SER1141 |
| B | LEU1143 |
| B | ASP1145 |
| B | VAL1153 |
| B | CYS1155 |
| B | TYR1211 |
| B | ARG1214 |
| B | PHE1215 |
| B | LYS1219 |
| B | EDO1308 |
| site_id | AD6 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 1302 |
| Chain | Residue |
| B | CYS1042 |
| B | CYS1031 |
| B | CYS1033 |
| B | CYS1037 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 1303 |
| Chain | Residue |
| B | CYS1037 |
| B | CYS1074 |
| B | CYS1080 |
| B | CYS1084 |
| site_id | AD8 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 1304 |
| Chain | Residue |
| B | CYS1031 |
| B | CYS1044 |
| B | CYS1074 |
| B | CYS1078 |
| site_id | AD9 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 1305 |
| Chain | Residue |
| B | CYS1172 |
| B | CYS1225 |
| B | CYS1227 |
| B | CYS1232 |
| site_id | AE1 |
| Number of Residues | 13 |
| Details | binding site for residue SAH B 1306 |
| Chain | Residue |
| B | MET1105 |
| B | TRP1107 |
| B | SER1141 |
| B | TYR1142 |
| B | ARG1166 |
| B | ASN1169 |
| B | HIS1170 |
| B | TYR1211 |
| B | PHE1223 |
| B | CYS1225 |
| B | ARG1226 |
| B | HOH1442 |
| B | HOH1476 |
| site_id | AE2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 1307 |
| Chain | Residue |
| B | ASP1056 |
| B | ARG1087 |
| B | ASN1091 |
| B | ARG1094 |
| B | HOH1567 |
| site_id | AE3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 1308 |
| Chain | Residue |
| B | ASP1210 |
| B | TYR1211 |
| B | JDG1301 |
| B | HOH1519 |
| site_id | AE4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 1309 |
| Chain | Residue |
| B | ASN1075 |
| B | HIS1076 |
| B | ARG1082 |
| B | ARG1087 |
| B | GLN1090 |
| B | HOH1518 |
| site_id | AE5 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 1310 |
| Chain | Residue |
| B | ASP1054 |
| B | LYS1055 |
| B | ARG1085 |
| B | HOH1403 |
| site_id | AE6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 1311 |
| Chain | Residue |
| B | CYS1033 |
| B | ILE1034 |
| B | ASP1035 |
| B | SER1039 |
| B | ASN1041 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 34 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | CYS1031 | |
| A | MET1105 | |
| A | TYR1142 | |
| A | ASN1169 | |
| A | CYS1172 | |
| A | CYS1225 | |
| A | ARG1226 | |
| A | CYS1227 | |
| A | CYS1232 | |
| B | CYS1031 | |
| B | CYS1033 | |
| A | CYS1033 | |
| B | CYS1037 | |
| B | CYS1042 | |
| B | CYS1044 | |
| B | CYS1074 | |
| B | CYS1078 | |
| B | CYS1080 | |
| B | CYS1084 | |
| B | MET1105 | |
| B | TYR1142 | |
| B | ASN1169 | |
| A | CYS1037 | |
| B | CYS1172 | |
| B | CYS1225 | |
| B | ARG1226 | |
| B | CYS1227 | |
| B | CYS1232 | |
| A | CYS1042 | |
| A | CYS1044 | |
| A | CYS1074 | |
| A | CYS1078 | |
| A | CYS1080 | |
| A | CYS1084 | |
| Chain | Residue | Details |
| A | TYR1124 | |
| B | TYR1124 | |
| Chain | Residue | Details |
| A | SER1017 | |
| B | SER1017 | |
