6MAC
Ternary structure of GDF11 bound to ActRIIB-ECD and Alk5-ECD
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Growth/differentiation factor 11 | polymer | 108 | 12357.2 | 1 | UniProt (O95390) Pfam (PF00019) In PDB | Homo sapiens (Human) | GDF-11,Bone morphogenetic protein 11,BMP-11 |
| 2 | C | Activin receptor type-2B | polymer | 95 | 11244.4 | 1 | UniProt (P38445) Pfam (PF01064) In PDB | Rattus norvegicus (Rat) | Activin receptor type IIB,ACTR-IIB |
| 3 | K | TGF-beta receptor type-1 | polymer | 80 | 8857.2 | 1 | UniProt (P36897) Pfam (PF01064) In PDB | Homo sapiens (Human) | TGFR-1,Activin A receptor type II-like protein kinase of 53kD,Activin receptor-like kinase 5,ALK5,Serine/threonine-protein kinase receptor R4,SKR4,TGF-beta type I receptor,Transforming growth factor-beta receptor type I,TbetaR-I |
| 4 | C | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 5 | water | water | 18.0 | 18 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 32458.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 442.4 | |
| All* | Total formula weight | 32901.2 |
