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6M93

Monophosphorylated pSer33 b-Catenin peptide, b-TrCP/Skp1, NRX-1933 ternary complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
F-box/WD repeat-containing protein 1Apolymer43249418.41UniProt (Q9Y297)
Pfam (PF12937)
Pfam (PF00400)
Homo sapiens (Human)E3RSIkappaB,Epididymis tissue protein Li 2a,F-box and WD repeats protein beta-TrCP,pIkappaBalpha-E3 receptor subunit
2B
(B)
S-phase kinase-associated protein 1polymer14416459.71UniProt (P63208)
Pfam (PF01466)
Pfam (PF03931)
Homo sapiens (Human)Cyclin-A/CDK2-associated protein p19,p19A,Organ of Corti protein 2,OCP-2,Organ of Corti protein II,OCP-II,RNA polymerase II elongation factor-like protein,SIII,Transcription elongation factor B polypeptide 1-like,p19skp1
3C
(C)
Catenin beta-1polymer333544.71UniProt (P35222)Homo sapiensBeta-catenin
4D
(A)
2-oxo-N-[3-(1H-tetrazol-5-yl)phenyl]-6-(trifluoromethyl)-1,2-dihydropyridine-3-carboxamidenon-polymer350.31Chemie (J8Y)
5E
(A)
PHOSPHATE IONnon-polymer95.01Chemie (PO4)
6F, G
(A, C)
waterwater18.014Chemie (HOH)
Sequence modifications
A: 139 - 569 (UniProt: Q9Y297)
PDBExternal DatabaseDetails
Ser 138-expression tag
B: 2 - 145 (UniProt: P63208)
PDBExternal DatabaseDetails
-Asp 37deletion
-Asp 38deletion
-Glu 39deletion
-Gly 40deletion
-Asp 41deletion
-Asp 42deletion
-Pro 71deletion
-Pro 72deletion
-Glu 73deletion
-Asp 74deletion
-Asp 75deletion
-Glu 76deletion
-Asn 77deletion
-Lys 78deletion
-Glu 79deletion
-Lys 80deletion
-Arg 81deletion
-Thr 82deletion
C: 17 - 48 (UniProt: P35222)
PDBExternal DatabaseDetails
Cys 16-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight69422.9
Non-Polymers*Number of molecules2
Total formula weight445.2
All*Total formula weight69868.1
*Water molecules are not included.

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PDB entries from 2024-11-06

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