6M93
Monophosphorylated pSer33 b-Catenin peptide, b-TrCP/Skp1, NRX-1933 ternary complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (A) | F-box/WD repeat-containing protein 1A | polymer | 432 | 49418.4 | 1 | UniProt (Q9Y297) Pfam (PF12937) Pfam (PF00400) | Homo sapiens (Human) | E3RSIkappaB,Epididymis tissue protein Li 2a,F-box and WD repeats protein beta-TrCP,pIkappaBalpha-E3 receptor subunit |
2 | B (B) | S-phase kinase-associated protein 1 | polymer | 144 | 16459.7 | 1 | UniProt (P63208) Pfam (PF01466) Pfam (PF03931) | Homo sapiens (Human) | Cyclin-A/CDK2-associated protein p19,p19A,Organ of Corti protein 2,OCP-2,Organ of Corti protein II,OCP-II,RNA polymerase II elongation factor-like protein,SIII,Transcription elongation factor B polypeptide 1-like,p19skp1 |
3 | C (C) | Catenin beta-1 | polymer | 33 | 3544.7 | 1 | UniProt (P35222) | Homo sapiens | Beta-catenin |
4 | D (A) | 2-oxo-N-[3-(1H-tetrazol-5-yl)phenyl]-6-(trifluoromethyl)-1,2-dihydropyridine-3-carboxamide | non-polymer | 350.3 | 1 | Chemie (J8Y) | |||
5 | E (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
6 | F, G (A, C) | water | water | 18.0 | 14 | Chemie (HOH) |
Sequence modifications
A: 139 - 569 (UniProt: Q9Y297)
B: 2 - 145 (UniProt: P63208)
C: 17 - 48 (UniProt: P35222)
PDB | External Database | Details |
---|---|---|
Ser 138 | - | expression tag |
PDB | External Database | Details |
---|---|---|
- | Asp 37 | deletion |
- | Asp 38 | deletion |
- | Glu 39 | deletion |
- | Gly 40 | deletion |
- | Asp 41 | deletion |
- | Asp 42 | deletion |
- | Pro 71 | deletion |
- | Pro 72 | deletion |
- | Glu 73 | deletion |
- | Asp 74 | deletion |
- | Asp 75 | deletion |
- | Glu 76 | deletion |
- | Asn 77 | deletion |
- | Lys 78 | deletion |
- | Glu 79 | deletion |
- | Lys 80 | deletion |
- | Arg 81 | deletion |
- | Thr 82 | deletion |
PDB | External Database | Details |
---|---|---|
Cys 16 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 69422.9 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 445.2 | |
All* | Total formula weight | 69868.1 |