6M93
Monophosphorylated pSer33 b-Catenin peptide, b-TrCP/Skp1, NRX-1933 ternary complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0006511 | biological_process | ubiquitin-dependent protein catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | binding site for residue J8Y A 601 |
| Chain | Residue |
| A | ARG330 |
| A | ALA434 |
| A | SER448 |
| C | ILE35 |
| C | HIS36 |
| C | SER37 |
| A | LEU340 |
| A | ASN341 |
| A | THR342 |
| A | ASN394 |
| A | GLY408 |
| A | ARG431 |
| A | GLY432 |
| A | ILE433 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue PO4 A 602 |
| Chain | Residue |
| A | ARG477 |
| A | PHE478 |
| A | GLN526 |
| A | PHE527 |
| A | HOH707 |
Functional Information from PROSITE/UniProt
| site_id | PS00678 |
| Number of Residues | 15 |
| Details | WD_REPEATS_1 Trp-Asp (WD) repeats signature. IITGssDsTVRVWDV |
| Chain | Residue | Details |
| A | ILE320-VAL334 | |
| A | MET360-MET374 | |
| A | ILE403-THR417 | |
| A | VAL443-ILE457 | |
| A | ILE483-LEU497 | |
| A | ILE532-PHE546 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine; by GSK3-beta; alternate => ECO:0000269|PubMed:12027456 |
| Chain | Residue | Details |
| C | SER23 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine; by GSK3-beta => ECO:0000269|PubMed:12027456 |
| Chain | Residue | Details |
| C | SER29 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine; by GSK3-beta and HIPK2 => ECO:0000269|PubMed:20307497, ECO:0000269|PubMed:25169422 |
| Chain | Residue | Details |
| C | SEP33 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine; by GSK3-beta and HIPK2 => ECO:0000269|PubMed:20307497 |
| Chain | Residue | Details |
| C | SER37 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine; by GSK3-beta => ECO:0000269|PubMed:12027456 |
| Chain | Residue | Details |
| C | THR41 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0000269|PubMed:12051714 |
| Chain | Residue | Details |
| C | SER45 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | CARBOHYD: O-linked (GlcNAc) serine; alternate => ECO:0000269|PubMed:24342833 |
| Chain | Residue | Details |
| C | SER23 |
