6M8Q
Cleavage and Polyadenylation Specificity Factor Subunit 3 (CPSF3) in complex with NVP-LTM531
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Cleavage and polyadenylation specificity factor subunit 3 | polymer | 478 | 54343.1 | 2 | UniProt (Q9UKF6) Pfam (PF00753) Pfam (PF10996) Pfam (PF07521) In PDB | Homo sapiens (Human) | Cleavage and polyadenylation specificity factor 73 kDa subunit,CPSF 73 kDa subunit,mRNA 3'-end-processing endonuclease CPSF-73 |
2 | A, B | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
3 | A, B | N-{3,5-dichloro-2-hydroxy-4-[2-(4-methylpiperazin-1-yl)ethoxy]benzene-1-carbonyl}-L-phenylalanine | non-polymer | 496.4 | 2 | Chemie (JBG) | |||
4 | A, B | PHOSPHATE ION | non-polymer | 95.0 | 3 | Chemie (PO4) | |||
5 | water | water | 18.0 | 484 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 459 (UniProt: Q9UKF6)
PDB | External Database | Details |
---|---|---|
Gly -18 | - | expression tag |
Ser -17 | - | expression tag |
Ser -16 | - | expression tag |
His -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
Ser -9 | - | expression tag |
Ser -8 | - | expression tag |
Gly -7 | - | expression tag |
Leu -6 | - | expression tag |
Val -5 | - | expression tag |
Pro -4 | - | expression tag |
Arg -3 | - | expression tag |
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 108686.1 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 1539.3 | |
All* | Total formula weight | 110225.5 |