6M6F

Solution structure of disulfide bond mutaion of the core domain of Fibroblast growth factor 21 (FGF21)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Fibroblast growth factor 21	polymer	129	14104.0	1	UniProt (Q9NSA1) Pfam (PF00167)	Homo sapiens (Human)	FGF-21

Sequence modifications

A: 13 - 136 (UniProt: Q9NSA1)

PDB	External Database	Details
Ser 23	Asp 52	engineered mutation
Gly 24	Asp 53	engineered mutation
Pro 25	Ala 54	engineered mutation
His 26	Gln 55	engineered mutation
Gly 27	-	insertion
Leu 28	Gln 56	engineered mutation
Ser 29	Thr 57	engineered mutation
Ser 30	Glu 58	engineered mutation
Cys 31	Ala 59	engineered mutation
Cys 43	Gly 71	engineered mutation
Leu 137	-	expression tag
Pro 138	-	expression tag
Leu 139	-	expression tag
Pro 140	-	expression tag
Gly 141	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	14104.0
All*	Total formula weight	14104.0

*Water molecules are not included.