6LKQ
The Structural Basis for Inhibition of Ribosomal Translocation by Viomycin
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (A) | 30S ribosomal protein S2 | polymer | 218 | 24253.9 | 1 | UniProt (C3TPN2) Pfam (PF00318) | Escherichia coli | |
2 | B (B) | 30S ribosomal protein S3 | polymer | 206 | 23078.8 | 1 | UniProt (A0A376HTV6) | Escherichia coli | |
3 | C (C) | 30S ribosomal protein S4 | polymer | 205 | 23383.0 | 1 | UniProt (A0A4P8BV83) Pfam (PF00163) Pfam (PF01479) | Escherichia coli | |
4 | D (D) | 30S ribosomal protein S5 | polymer | 150 | 15804.3 | 1 | UniProt (F4SQ30) | Escherichia coli | |
5 | E (E) | 30S ribosomal protein S6 | polymer | 100 | 11669.4 | 1 | UniProt (A0A3L2GT12) | Escherichia coli | |
6 | F (F) | 30S ribosomal protein S7 | polymer | 151 | 16861.5 | 1 | UniProt (D6I218) | Escherichia coli | |
7 | G (G) | 30S ribosomal protein S8 | polymer | 129 | 14015.4 | 1 | UniProt (U9ZUM7) | Escherichia coli | |
8 | H (H) | 30S ribosomal protein S9 | polymer | 127 | 14554.9 | 1 | UniProt (D8A919) Pfam (PF00380) | Escherichia coli | |
9 | I (I) | 30S ribosomal protein S10 | polymer | 98 | 11197.0 | 1 | UniProt (A0A5B9AU26) | Escherichia coli | |
10 | J (J) | 30S ribosomal protein S11 | polymer | 117 | 12487.2 | 1 | UniProt (A0A4P8B3R1) | Escherichia coli | |
11 | K (K) | 30S ribosomal protein S12 | polymer | 123 | 13637.0 | 1 | UniProt (L3C3P4) | Escherichia coli | |
12 | L (L) | 30S ribosomal protein S13 | polymer | 114 | 12625.8 | 1 | UniProt (A0A069XLE9) | Escherichia coli | |
13 | M (M) | 30S ribosomal protein S14 | polymer | 100 | 11489.4 | 1 | UniProt (A0A090BZT4) Pfam (PF00253) | Escherichia coli | |
14 | N (N) | 30S ribosomal protein S15 | polymer | 88 | 10159.6 | 1 | UniProt (A0A029IK47) | Escherichia coli | |
15 | O (O) | 30S ribosomal protein S16 | polymer | 82 | 9207.6 | 1 | UniProt (A0A029IMB2) | Escherichia coli | |
16 | P (P) | 30S ribosomal protein S17 | polymer | 80 | 9263.9 | 1 | UniProt (T6LV72) | Escherichia coli | |
17 | Q (Q) | 30S ribosomal protein S18 | polymer | 55 | 6466.5 | 1 | UniProt (E9TDX6) | Escherichia coli | |
18 | R (R) | 30S ribosomal protein S19 | polymer | 79 | 9057.6 | 1 | UniProt (S1EA57) | Escherichia coli | |
19 | S (S) | 30S ribosomal protein S20 | polymer | 85 | 9506.2 | 1 | UniProt (D7ZAS2) | Escherichia coli | |
20 | T (T) | 30S ribosomal protein S21 | polymer | 51 | 6067.1 | 1 | UniProt (A0A5C9AJ78) Pfam (PF01165) | Escherichia coli | |
21 | U (U) | 50S ribosomal protein L2 | polymer | 271 | 29663.2 | 1 | UniProt (A0A1X3LPI5) | Escherichia coli | |
22 | V (V) | 50S ribosomal protein L3 | polymer | 209 | 22277.5 | 1 | UniProt (I2X6U5) | Escherichia coli | |
23 | W (W) | 50S ribosomal protein L4 | polymer | 201 | 22121.6 | 1 | UniProt (L3C159) | Escherichia coli | |
24 | X (X) | 50S ribosomal protein L5 | polymer | 177 | 20073.2 | 1 | UniProt (H4IXW7) | Escherichia coli | |
25 | Y (Y) | 50S ribosomal protein L6 | polymer | 176 | 18801.6 | 1 | UniProt (V0AIU3) | Escherichia coli | |
26 | Z (Z) | 50S ribosomal protein L11 | polymer | 141 | 14763.2 | 1 | UniProt (H4J053) | Escherichia coli | |
27 | AA (0) | 50S ribosomal protein L13 | polymer | 142 | 16050.6 | 1 | UniProt (S1EW51) | Escherichia coli | |
28 | BA (1) | 50S ribosomal protein L14 | polymer | 122 | 13451.9 | 1 | UniProt (V0YSM1) | Escherichia coli | |
29 | CA (2) | 50S ribosomal protein L15 | polymer | 143 | 14877.3 | 1 | UniProt (A0A037Y8L6) Pfam (PF00828) | Escherichia coli | |
30 | DA (3) | 50S ribosomal protein L16 | polymer | 136 | 15312.3 | 1 | UniProt (H4LI23) | Escherichia coli | |
31 | EA (4) | 50S ribosomal protein L17 | polymer | 120 | 13721.9 | 1 | UniProt (A0A1X3LC97) | Escherichia coli | |
32 | FA (5) | 50S ribosomal protein L18 | polymer | 116 | 12663.5 | 1 | UniProt (H4JDL8) | Escherichia coli | |
33 | GA (6) | 50S ribosomal protein L19 | polymer | 114 | 13028.1 | 1 | UniProt (A0A0F6C7T5) | Escherichia coli | |
34 | HA (8) | 50S ribosomal protein L20 | polymer | 117 | 13396.8 | 1 | UniProt (V6FS92) | Escherichia coli | |
35 | IA (9) | 50S ribosomal protein L21 | polymer | 103 | 11586.4 | 1 | UniProt (L4V445) | Escherichia coli | |
36 | JA (a) | 50S ribosomal protein L22 | polymer | 110 | 12253.4 | 1 | UniProt (F4TL38) | Escherichia coli | |
37 | KA (b) | 50S ribosomal protein L23 | polymer | 93 | 10546.5 | 1 | UniProt (S1EUY1) | Escherichia coli | |
38 | LA (c) | 50S ribosomal protein L24 | polymer | 102 | 11078.9 | 1 | UniProt (F4TL32) | Escherichia coli | |
39 | MA (d) | 50S ribosomal protein L25 | polymer | 94 | 10713.5 | 1 | UniProt (D7Y4U5) | Escherichia coli | |
40 | NA (e) | 50S ribosomal protein L27 | polymer | 79 | 8476.7 | 1 | UniProt (A0A5D8K7F9) | Escherichia coli | |
41 | OA (f) | 50S ribosomal protein L28 | polymer | 77 | 8896.4 | 1 | UniProt (A0A5B7P765) | Escherichia coli | |
42 | PA (g) | 50S ribosomal protein L29 | polymer | 63 | 7286.5 | 1 | UniProt (I2X6R6) | Escherichia coli | |
43 | QA (h) | 50S ribosomal protein L30 | polymer | 58 | 6423.6 | 1 | UniProt (A0A073FR56) | Escherichia coli | |
44 | RA (i) | 50S ribosomal protein L32 | polymer | 56 | 6332.2 | 1 | UniProt (D7XI28) | Escherichia coli | |
45 | SA (j) | 50S ribosomal protein L33 | polymer | 50 | 5814.8 | 1 | UniProt (L3NSS9) | Escherichia coli | |
46 | TA (k) | 50S ribosomal protein L34 | polymer | 46 | 5397.5 | 1 | UniProt (A0A1X3IEM2) | Escherichia coli | |
47 | UA (l) | 50S ribosomal protein L35 | polymer | 64 | 7181.8 | 1 | UniProt (L3P377) | Escherichia coli | |
48 | VA (m) | 50S ribosomal protein L36 | polymer | 38 | 4377.4 | 1 | UniProt (F4V714) | Escherichia coli | |
49 | WA (n) | 50S ribosomal protein L10 | polymer | 163 | 17634.5 | 1 | UniProt (A0A1X3LA41) | Escherichia coli | |
50 | AB, XA, YA, ZA (o, p, q, r) | 50S ribosomal protein L7/L12 | polymer | 30 | 3300.9 | 4 | UniProt (A0A4C9D1M4) Pfam (PF16320) | Escherichia coli | |
51 | BB (s) | 16S ribosomal RNA | polymer | 1532 | 496563.1 | 1 | GenBank (1726022446) | Escherichia coli | |
52 | CB (t) | 23S ribosomal RNA | polymer | 2903 | 941306.2 | 1 | GenBank (1036415628) | Escherichia coli | |
53 | DB (u) | 5S ribosomal RNA | polymer | 118 | 38177.8 | 1 | GenBank (1727529157) | Escherichia coli | |
54 | EB (v) | Peptide chain release factor 3 | polymer | 525 | 59152.4 | 1 | UniProt (C3SE77) Pfam (PF22042) Pfam (PF16658) Pfam (PF00009) | Escherichia coli | RF-3 |
55 | FB (w) | messenger RNA | polymer | 6 | 1900.2 | 1 | Escherichia coli | ||
56 | GB, HB, IB, JB, KB (y, z, 7, AA, BA) | Viomycin | polymer | 6 | 703.7 | 5 | BIRD (PRD_000226) | synthetic construct |
Sequence modifications
n: 1 - 163 (UniProt: A0A1X3LA41)
PDB | External Database | Details |
---|---|---|
Leu 85 | Ser 85 | conflict |
Glu 160 | Asp 160 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 63 |
Total formula weight | 2192810.3 | |
All* | Total formula weight | 2192810.3 |