6LJM
Crystal structure of human Sirt5 in complex with the fluorogenic tetrapeptide substrate P13
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | NAD-dependent protein deacylase sirtuin-5, mitochondrial | polymer | 272 | 29568.7 | 1 | UniProt (Q9NXA8) Pfam (PF02146) In PDB | Homo sapiens (human) | Regulatory protein SIR2 homolog 5,SIR2-like protein 5 |
2 | B | ACE-SER-LEU-GLY-SLL | polymer | 5 | 529.6 | 1 | synthetic construct | ||
3 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
4 | B | 7-AMINO-4-METHYL-CHROMEN-2-ONE | non-polymer | 175.2 | 1 | Chemie (MCM) | |||
5 | water | water | 18.0 | 290 | Chemie (HOH) |
Sequence modifications
A: 34 - 302 (UniProt: Q9NXA8)
PDB | External Database | Details |
---|---|---|
Gln 31 | - | expression tag |
Ala 32 | - | expression tag |
Ser 33 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 30098.3 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 240.6 | |
All* | Total formula weight | 30338.9 |