6LJM
Crystal structure of human Sirt5 in complex with the fluorogenic tetrapeptide substrate P13
Functional Information from GO Data
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1 |
Details | ACT_SITE: Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU00236, ECO:0000269|PubMed:22076378, ECO:0000269|PubMed:29180469 |
Chain | Residue | Details |
A | HIS158 |
site_id | SWS_FT_FI2 |
Number of Residues | 5 |
Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_03160, ECO:0000269|PubMed:22076378, ECO:0000269|PubMed:22767592, ECO:0000269|Ref.19 |
Chain | Residue | Details |
A | GLY58 | |
A | GLN140 | |
A | GLY249 | |
A | ASN275 | |
A | CYS293 |
site_id | SWS_FT_FI3 |
Number of Residues | 6 |
Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_03160 |
Chain | Residue | Details |
A | TYR102 | |
A | ARG105 | |
A | CYS166 | |
A | CYS169 | |
A | CYS207 | |
A | CYS212 |