6LE5

Crystal structure of the mitochondrial calcium uptake 1 and 2 heterodimer (MICU1-MICU2 heterodimer) in an apo state

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D, E, G	Calcium uptake protein 1, mitochondrial	polymer	348	40204.9	4	UniProt (Q9BPX6) Pfam (PF13202) In PDB	Homo sapiens (Human)	Atopy-related autoantigen CALC,ara CALC,Calcium-binding atopy-related autoantigen 1
2	B, C, F, H	Calcium uptake protein 2, mitochondrial	polymer	325	39314.7	4	UniProt (Q8IYU8) In PDB	Homo sapiens (Human)	EF-hand domain-containing family member A1

Sequence modifications

B, C, F, H: 84 - 401 (UniProt: Q8IYU8)

PDB	External Database	Details
His 77	-	expression tag
His 78	-	expression tag
His 79	-	expression tag
His 80	-	expression tag
His 81	-	expression tag
His 82	-	expression tag
Mse 83	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	318078.3
All*	Total formula weight	318078.3

*Water molecules are not included.