6LE5

Crystal structure of the mitochondrial calcium uptake 1 and 2 heterodimer (MICU1-MICU2 heterodimer) in an apo state

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005509	molecular_function	calcium ion binding
A	0006851	biological_process	mitochondrial calcium ion transmembrane transport
B	0005509	molecular_function	calcium ion binding
B	0006851	biological_process	mitochondrial calcium ion transmembrane transport
C	0005509	molecular_function	calcium ion binding
C	0006851	biological_process	mitochondrial calcium ion transmembrane transport
D	0005509	molecular_function	calcium ion binding
D	0006851	biological_process	mitochondrial calcium ion transmembrane transport
E	0005509	molecular_function	calcium ion binding
E	0006851	biological_process	mitochondrial calcium ion transmembrane transport
F	0005509	molecular_function	calcium ion binding
F	0006851	biological_process	mitochondrial calcium ion transmembrane transport
G	0005509	molecular_function	calcium ion binding
G	0006851	biological_process	mitochondrial calcium ion transmembrane transport
H	0005509	molecular_function	calcium ion binding
H	0006851	biological_process	mitochondrial calcium ion transmembrane transport

Functional Information from PROSITE/UniProt

site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DLNGDGEVDmeEF

Chain	Residue	Details
A	ASP231-PHE243
A	ASP421-PHE433

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648

Chain	Residue	Details
B	SER205
A	GLU432
D	ASP231
D	ASN233
D	ASP235
D	GLU237
D	GLU242
D	ASP421
D	ASP423
D	ASN425
D	GLU427
C	SER205
D	GLU432
E	ASP231
E	ASN233
E	ASP235
E	GLU237
E	GLU242
E	ASP421
E	ASP423
E	ASN425
E	GLU427
F	SER205
E	GLU432
G	ASP231
G	ASN233
G	ASP235
G	GLU237
G	GLU242
G	ASP421
G	ASP423
G	ASN425
G	GLU427
H	SER205
G	GLU432
A	GLU242
A	ASP421
A	ASP423
A	ASN425
A	GLU427

---