6LAE
Crystal structure of the DNA-binding domain of human XPA in complex with DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | DNA repair protein complementing XP-A cells | polymer | 145 | 17473.2 | 2 | UniProt (P23025) Pfam (PF01286) Pfam (PF05181) | Homo sapiens (Human) | Xeroderma pigmentosum group A-complementing protein |
| 2 | C (C) | DNA (5'-D(P*GP*CP*AP*TP*CP*TP*CP*GP*CP*CP*T)-3') | polymer | 11 | 3285.1 | 1 | Homo sapiens | ||
| 3 | D (D) | DNA (5'-D(P*TP*GP*GP*CP*GP*AP*GP*AP*TP*GP*C)-3') | polymer | 11 | 3414.2 | 1 | Homo sapiens | ||
| 4 | E, F (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 5 | G, H (A, B) | water | water | 18.0 | 6 | Chemie (HOH) |
Sequence modifications
A, B: 98 - 239 (UniProt: P23025)
| PDB | External Database | Details |
|---|---|---|
| Gly 95 | - | expression tag |
| Ser 96 | - | expression tag |
| His 97 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 41645.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 130.8 | |
| All* | Total formula weight | 41776.5 |
