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6L71

Sirtuin 2 demyristoylation native intermediate I & II mixture

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
NAD-dependent protein deacetylase sirtuin-2polymer30434404.71UniProt (Q8IXJ6)
Pfam (PF02146)
Homo sapiens (Human)Regulatory protein SIR2 homolog 2,SIR2-like protein 2
2B
(C)
PRO-ARG-LYS-GLN-LEU-ALApolymer6713.91synthetic construct
3C
(A)
NICOTINAMIDEnon-polymer122.11Chemie (NCA)
4D
(C)
[[(2S,3aS,5S,6R,6aS)-2-dodecyl-6-oxidanyl-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-5-yl]methoxy-oxidanyl-phosphoryl] [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl hydrogen phosphatenon-polymer739.61Chemie (YOY)
5E
(C)
[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2R,3S,4R,5S)-3,4-bis(oxidanyl)-5-tetradecoxy-oxolan-2-yl]methyl hydrogen phosphatenon-polymer755.71Chemie (YDD)
6F, G
(A, C)
waterwater18.0223Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight35118.6
Non-Polymers*Number of molecules3
Total formula weight1617.5
All*Total formula weight36736.0
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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