6L71
Sirtuin 2 demyristoylation native intermediate I & II mixture
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | binding site for residue NCA A 401 |
| Chain | Residue |
| A | ALA85 |
| C | YDD402 |
| C | HOH501 |
| A | ILE93 |
| A | PRO94 |
| A | PHE96 |
| A | ASN168 |
| A | ILE169 |
| A | ASP170 |
| A | HOH542 |
| C | YOY401 |
| site_id | AC2 |
| Number of Residues | 28 |
| Details | binding site for residue YOY C 401 |
| Chain | Residue |
| A | GLY84 |
| A | ALA85 |
| A | GLY86 |
| A | THR89 |
| A | ASP95 |
| A | PHE96 |
| A | ARG97 |
| A | PRO140 |
| A | GLN167 |
| A | ILE169 |
| A | HIS187 |
| A | PHE190 |
| A | VAL233 |
| A | PHE235 |
| A | GLY261 |
| A | THR262 |
| A | SER263 |
| A | ASN286 |
| A | LYS287 |
| A | GLU288 |
| A | GLY322 |
| A | GLU323 |
| A | CYS324 |
| A | NCA401 |
| C | LYS9 |
| C | YDD402 |
| C | HOH501 |
| C | HOH502 |
| site_id | AC3 |
| Number of Residues | 26 |
| Details | binding site for residue YDD C 402 |
| Chain | Residue |
| A | GLY84 |
| A | ALA85 |
| A | GLY86 |
| A | THR89 |
| A | ASP95 |
| A | PHE96 |
| A | ARG97 |
| A | PHE119 |
| A | GLN167 |
| A | HIS187 |
| A | VAL233 |
| A | PHE235 |
| A | GLY261 |
| A | THR262 |
| A | SER263 |
| A | ASN286 |
| A | LYS287 |
| A | GLU288 |
| A | GLY322 |
| A | GLU323 |
| A | CYS324 |
| A | NCA401 |
| C | LYS9 |
| C | YOY401 |
| C | HOH501 |
| C | HOH502 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU00236 |
| Chain | Residue | Details |
| A | HIS187 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:25672491, ECO:0007744|PDB:4RMG |
| Chain | Residue | Details |
| A | ASP95 | |
| A | GLN167 | |
| A | THR262 | |
| A | ASN286 | |
| A | CYS324 | |
| A | ALA85 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00236, ECO:0000269|PubMed:11427894, ECO:0000269|PubMed:23454361, ECO:0000269|PubMed:24389023, ECO:0000269|PubMed:25672491, ECO:0000269|PubMed:25704306, ECO:0007744|PDB:4R8M |
| Chain | Residue | Details |
| A | CYS195 | |
| A | CYS200 | |
| A | CYS221 | |
| A | CYS224 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q5RJQ4 |
| Chain | Residue | Details |
| A | SER100 | |
| A | SER207 | |
| A | SER53 |
