6KWX

cryo-EM structure of human PA200

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Proteasome activator complex subunit 4	polymer	1878	215774.9	1	UniProt (Q14997) Pfam (PF16507) Pfam (PF23096) Pfam (PF11919)	Homo sapiens (Human)	Proteasome activator PA200
2	B (A)	[(1~{S},2~{R},3~{R},4~{S},5~{S},6~{R})-2-[oxidanyl(phosphonooxy)phosphoryl]oxy-3,4,5,6-tetraphosphonooxy-cyclohexyl] phosphono hydrogen phosphate	non-polymer		820.0	1	Chemie (K0W)
3	C (A)	INOSITOL HEXAKISPHOSPHATE	non-polymer		660.0	1	Chemie (IHP)

Sequence modifications

A: 1 - 1843 (UniProt: Q14997)

PDB	External Database	Details
Met -34	-	initiating methionine
Gly -33	-	expression tag
Thr -32	-	expression tag
Thr -31	-	expression tag
Arg -30	-	expression tag
Ser -29	-	expression tag
Thr -28	-	expression tag
Met -27	-	expression tag
Ser -26	-	expression tag
Tyr -25	-	expression tag
Tyr -24	-	expression tag
His -23	-	expression tag
His -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
Asp -17	-	expression tag
Tyr -16	-	expression tag
Asp -15	-	expression tag
Ile -14	-	expression tag
Pro -13	-	expression tag
Thr -12	-	expression tag
Thr -11	-	expression tag
Glu -10	-	expression tag
Asn -9	-	expression tag
Leu -8	-	expression tag
Tyr -7	-	expression tag
Phe -6	-	expression tag
Gln -5	-	expression tag
Gly -4	-	expression tag
Ala -3	-	expression tag
Met -2	-	expression tag
Asp -1	-	expression tag
Pro 0	-	expression tag
Ile 821	Leu 821	conflict
Leu 822	Ile 822	conflict

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	215774.9
Non-Polymers*	Number of molecules	2
	Total formula weight	1480.0
All*	Total formula weight	217254.9

*Water molecules are not included.