6KRO
Tankyrase-2 in complex with RK-582
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tankyrase-2 | polymer | 168 | 19150.6 | 1 | UniProt (Q9H2K2) Pfam (PF00644) | Homo sapiens (Human) | TANK2,ADP-ribosyltransferase diphtheria toxin-like 6,ARTD6,Poly [ADP-ribose] polymerase 5B,TNKS-2,TRF1-interacting ankyrin-related ADP-ribose polymerase 2,Tankyrase II,Tankyrase-like protein,Tankyrase-related protein |
| 2 | B (B) | Tankyrase-2 | polymer | 48 | 5364.0 | 1 | UniProt (Q9H2K2) | Homo sapiens (Human) | |
| 3 | C (A) | 6-[(2S,6R)-2,6-dimethylmorpholin-4-yl]-4-fluoranyl-1-methyl-1'-(8-methyl-4-oxidanylidene-3,5,6,7-tetrahydropyrido[2,3-d]pyrimidin-2-yl)spiro[indole-3,4'-piperidine]-2-one | non-polymer | 510.6 | 1 | Chemie (DU9) | |||
| 4 | D (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 5 | E (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 6 | F, G (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 7 | H, I (A, B) | water | water | 18.0 | 113 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 24514.7 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 855.2 | |
| All* | Total formula weight | 25369.8 |
