6KN0
caspase-1 P20/P10 C285A in complex with human GSDMD-C domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C | Caspase-1 | polymer | 167 | 18778.7 | 2 | UniProt (P29466) Pfam (PF00656) In PDB | Homo sapiens (Human) | CASP-1,Interleukin-1 beta convertase,IL-1BC,Interleukin-1 beta-converting enzyme,IL-1 beta-converting enzyme,p45 |
| 2 | B, D | Caspase-1 | polymer | 88 | 10258.8 | 2 | UniProt (P29466) Pfam (PF00656) In PDB | Homo sapiens (Human) | CASP-1,Interleukin-1 beta convertase,IL-1BC,Interleukin-1 beta-converting enzyme,IL-1 beta-converting enzyme,p45 |
| 3 | E, F | Gasdermin-D | polymer | 198 | 21250.3 | 2 | UniProt (P57764) Pfam (PF17708) In PDB | Homo sapiens (Human) | Gasdermin domain-containing protein 1 |
Sequence modifications
A, C: 131 - 297 (UniProt: P29466)
| PDB | External Database | Details |
|---|---|---|
| Ala 285 | Cys 285 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 100575.4 | |
| All* | Total formula weight | 100575.4 |
