6KM7

The structural basis for the internal interaction in RBBP5

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Retinoblastoma-binding protein 5	polymer	317	35182.2	2	UniProt (Q15291) Pfam (PF00400)	Homo sapiens (Human)	WD40 propeller, RBBP-5,Retinoblastoma-binding protein RBQ-3
2	C, D (C, D)	Retinoblastoma-binding protein 5	polymer	69	7495.3	2	UniProt (Q15291)	Homo sapiens (Human)	RBBP-5,Retinoblastoma-binding protein RBQ-3
3	E, F, H, I, J... (A, B)	SULFATE ION	non-polymer		96.1	8	Chemie (SO4)
4	G (A)	NONAETHYLENE GLYCOL	non-polymer		414.5	1	Chemie (2PE)
5	N (B)	HEXAETHYLENE GLYCOL	non-polymer		282.3	1	Chemie (P6G)
6	O (C)	TETRAETHYLENE GLYCOL	non-polymer		194.2	1	Chemie (PG4)
7	P, Q, R, S (A, B, C, D)	water	water		18.0	479	Chemie (HOH)

Sequence modifications

A, B: 10 - 325 (UniProt: Q15291)

PDB	External Database	Details
Ser 9	-	expression tag

C, D: 390 - 480 (UniProt: Q15291)

PDB	External Database	Details
-	Asp 421	deletion
-	Ala 422	deletion
-	Val 423	deletion
-	Gln 424	deletion
-	Thr 425	deletion
-	Ser 426	deletion
-	Leu 427	deletion
-	Met 428	deletion
-	Asp 429	deletion
-	Glu 430	deletion
-	Gly 431	deletion
-	Ala 432	deletion
-	Ser 433	deletion
-	Ser 434	deletion
-	Glu 435	deletion
-	Lys 436	deletion
-	Lys 437	deletion
-	Arg 438	deletion
-	Gln 439	deletion
-	Ser 440	deletion
-	Ser 441	deletion
-	Ala 442	deletion

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	85355.0
Non-Polymers*	Number of molecules	11
	Total formula weight	1659.5
All*	Total formula weight	87014.6

*Water molecules are not included.