6KIY
Crystal structure of a thermostable aldo-keto reductase Tm1743 in complex with inhibitor Epalrestat
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Oxidoreductase, aldo/keto reductase family | polymer | 275 | 31490.0 | 1 | UniProt (Q9X265) Pfam (PF00248) | Thermotoga maritima MSB8 | |
| 2 | B (A) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 1 | Chemie (NAP) | |||
| 3 | C (A) | {5-[(2E)-2-methyl-3-phenylprop-2-en-1-ylidene]-4-oxo-2-thioxo-1,3-thiazolidin-3-yl}acetic acid | non-polymer | 319.4 | 1 | Chemie (EPR) | |||
| 4 | D (A) | water | water | 18.0 | 92 | Chemie (HOH) |
Sequence modifications
A: 1 - 274 (UniProt: Q9X265)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 31490.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1062.8 | |
| All* | Total formula weight | 32552.8 |
