6KHD
Crystal structure of CLK1 in complex with CX-4945
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Dual specificity protein kinase CLK1 | polymer | 484 | 57322.7 | 3 | UniProt (P49759) Pfam (PF00069) | Homo sapiens (Human) | CDC-like kinase 1 |
| 2 | D, E, F (A, B, C) | 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid | non-polymer | 349.8 | 3 | Chemie (3NG) | |||
| 3 | G, H, I (A, B, C) | water | water | 18.0 | 22 | Chemie (HOH) |
Sequence modifications
A, B, C: 1 - 484 (UniProt: P49759)
| PDB | External Database | Details |
|---|---|---|
| Ala 432 | Arg 432 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 171968.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1049.3 | |
| All* | Total formula weight | 173017.3 |
