6KDP
Crystal structure of human DNMT3B-DNMT3L complex (II)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, D) | DNA (cytosine-5)-methyltransferase 3B | polymer | 286 | 32715.9 | 2 | UniProt (Q9UBC3) Pfam (PF00145) | Homo sapiens (Human) | Dnmt3b,DNA methyltransferase HsaIIIB,M.HsaIIIB |
| 2 | B, C (B, C) | DNA (cytosine-5)-methyltransferase 3-like | polymer | 204 | 23627.1 | 2 | UniProt (Q9UJW3) | Homo sapiens (Human) | |
| 3 | E, G (A, D) | FORMIC ACID | non-polymer | 46.0 | 2 | Chemie (FMT) | |||
| 4 | F, H (A, D) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 2 | Chemie (SAH) | |||
| 5 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 111 | Chemie (HOH) |
Sequence modifications
A, D: 571 - 853 (UniProt: Q9UBC3)
B, C: 178 - 379 (UniProt: Q9UJW3)
| PDB | External Database | Details |
|---|---|---|
| Gly 568 | - | expression tag |
| His 569 | - | expression tag |
| Met 570 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 176 | - | expression tag |
| His 177 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 112685.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 860.9 | |
| All* | Total formula weight | 113546.8 |
