Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help

6KDP

Crystal structure of human DNMT3B-DNMT3L complex (II)

Functional Information from GO Data
ChainGOidnamespacecontents
A0008168molecular_functionmethyltransferase activity
D0008168molecular_functionmethyltransferase activity
Functional Information from PDB Data
site_idAC1
Number of Residues2
Detailsbinding site for residue FMT A 901
ChainResidue
AASN717
AGLY737

site_idAC2
Number of Residues16
Detailsbinding site for residue SAH A 902
ChainResidue
ACYS607
AASP627
AVAL628
AGLY648
APRO650
ALEU671
AARG832
ASER833
ATRP834
APHE581
AASP582
AGLY583
AILE584
ATHR586
ASER604
AGLU605

site_idAC3
Number of Residues3
Detailsbinding site for residue FMT D 901
ChainResidue
DASN717
DGLY737
DASN743

site_idAC4
Number of Residues16
Detailsbinding site for residue SAH D 902
ChainResidue
DPHE581
DASP582
DGLY583
DILE584
DTHR586
DSER604
DGLU605
DVAL606
DASP627
DVAL628
DARG629
DGLY648
DLEU671
DARG832
DSER833
DTRP834

Functional Information from PROSITE/UniProt
site_idPS00094
Number of Residues13
DetailsC5_MTASE_1 C-5 cytosine-specific DNA methylases active site. DlVigGsPCnDLS
ChainResidueDetails
AASP643-SER655

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsACT_SITE: ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU01016, ECO:0000255|PROSITE-ProRule:PRU10018
ChainResidueDetails
ACYS651
DCYS651

site_idSWS_FT_FI2
Number of Residues8
DetailsBINDING: BINDING => ECO:0000250|UniProtKB:Q9Y6K1
ChainResidueDetails
AASP582
AGLU605
AASP627
AARG832
DASP582
DGLU605
DASP627
DARG832

site_idSWS_FT_FI3
Number of Residues4
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733
ChainResidueDetails
ALYS617
DLYS617

229380

PDB entries from 2024-12-25

PDB statisticsPDBj update infoContact PDBjnumon